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    The seizure risk is also increased in patient taking Ultram concomitantly with selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs) or other tricyclic medications, such as cyclobenzaprine or promethazine, other opioids, monoamine oxidase inhibitors (MAOIs), neuroleptics or other medications that reduce the seizure threshold. The risk of convulsions may also be increased in patients with epilepsy, a history of seizures, or in patients who already have a risk for seizures, such as head trauma. There is also a suicide risk possible with Ultram treatment.
    Other drugs that have been reported to cause weight gain include diabetes medications (insulin, sulfonylureas, and thiazolidinediones), antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors. If you think a drug you are taking is causing weight gain, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Michelle McDermott, RPh
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    Other drugs that have been reported to cause weight gain include diabetes medications (insulin, sulfonylureas, and thiazolidinediones), antihypertensive drugs, certain hormonal contraceptives, corticosteroids, antihistamines, some chemotherapy regimens, and antiretroviral protease inhibitors. If you think a drug you are taking is causing weight gain, tell your health care provider. Do not stop any medication or change the dose without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Michelle McDermott, RPh
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