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If Ultram must be administered along with CNS depressants, caution is advised and a reduced dosage of Ultram may be necessary. Ultram 50 mg increases the risk of CNS and respiratory depression in patients receiving CNS depressants including alcohol, opioids, anesthetic medications, narcotics, phenothiazines, tranquilizers, or sedative hypnotics. Additive CNS depression is possible when Ultram is concomitantly used with these other medications and dangerous side effects may occur. For more specific information regarding the risk versus benefit of treatment with Ultram 50 mg, consult with you health care provider.
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