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A: Tramadol (Ultram) is a centrally acting analgesic with a unique, dual mechanism of action. It works as an opioid and also has weak inhibitory effects on the brain chemicals norepinephrine and serotonin. Withdrawal symptoms may include anxiety, sweating, nausea, tremors, diarrhea, upper respiratory symptoms, insomnia, pain, tingling, and rarely hallucinations. These symptoms can be worse in patients who have been previously dependent or chronically taking other opioid drugs (such as Vicodin). Experience suggests that withdrawal symptoms may be relieved by tapering the dosage of tramadol. The slower the tapering, the fewer withdrawal symptoms would be expected. With respect to the side effects you describe in your question, according to the package insert for tramadol, headache was reported in 18 percent and 32 percent of patients treated with immediate-release tramadol for seven and 90 days, respectively. Overuse of analgesics such as tramadol products by headache-prone patients frequently produces drug-induced rebound headache. In this case, overuse of tramadol products has been defined as taking three or more doses per day more often than three to five days per week. There is no information to suggest that tramadol can cause changes to the menstrual cycle. For more information, please consult with your health care provider and visit //www.everydayhealth.com/drugs/tramadol. Michelle McDermott, PharmD
Q: I have been on tramadol for 3-4 years now, and I am taking 300 to 400 mg per day. Is this harmful for my health? A: Chronic pain can be difficult to manage and if the cause of the pain is unable to be treated, the symptoms of pain may be well-controlled with the use of Ultram (tramadol) which is a medication used to manage moderate to severe pain. Ultram (tramadol) is eliminated mostly through the kidneys, but also goes through the liver, so your doctor should periodically monitor their function. Ultram (tramadol) was developed as an answer to avoiding dependence to pain medication, which opiates can have, but studies have found that the metabolite (what the drug turns into) of Ultram (tramadol) can also create some dependence by the user. Ultram (tramadol) does not help reduce the cause of pain. It just blocks the signal from going to the brain that causes the body to feel pain.
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Q: I have been on tramadol for 3-4 years now, and I am taking 300 to 400 mg per day. Is this harmful for my health? A: Chronic pain can be difficult to manage and if the cause of the pain is unable to be treated, the symptoms of pain may be well-controlled with the use of Ultram (tramadol) which is a medication used to manage moderate to severe pain. Ultram (tramadol) is eliminated mostly through the kidneys, but also goes through the liver, so your doctor should periodically monitor their function. Ultram (tramadol) was developed as an answer to avoiding dependence to pain medication, which opiates can have, but studies have found that the metabolite (what the drug turns into) of Ultram (tramadol) can also create some dependence by the user. Ultram (tramadol) does not help reduce the cause of pain. It just blocks the signal from going to the brain that causes the body to feel pain.
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